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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYROBPTYRO protein tyrosine kinase binding protein. (109 aa)    
Predicted Functional Partners:
TREM2
Triggering receptor expressed on myeloid cells 2.
   
 0.999
ITGB2
Integrin subunit beta 2.
   
  
 0.999
SYK
Spleen associated tyrosine kinase.
   
 0.997
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
   
 0.988
FCER1G
Fc fragment of IgE receptor Ig.
   
  
 0.981
HCST
Hematopoietic cell signal transducer.
   
 
 0.963
KLRD1
Killer cell lectin like receptor D1.
   
 0.953
ENSCWAP00000005868
annotation not available
   
 0.941
FYN
FYN proto-oncogene, Src family tyrosine kinase.
   
 0.926
KLRK1
Killer cell lectin like receptor K1.
   
 0.924
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.