Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLCG2Phospholipase C gamma 2. (1265 aa)    
Predicted Functional Partners:
BTK
Bruton tyrosine kinase.
   
 0.996
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.995
EGFR
Epidermal growth factor receptor.
    
 0.995
LCP2
Lymphocyte cytosolic protein 2.
   
 0.994
LAT
Linker for activation of T cells.
    
 0.993
SYK
Spleen associated tyrosine kinase.
   
 0.990
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.986
PDGFRB
Platelet derived growth factor receptor beta.
    
 0.986
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.985
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
   
 0.980
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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