Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPG11SPG11 vesicle trafficking associated, spatacsin. (2433 aa)    
Predicted Functional Partners:
ZFYVE26
Zinc finger FYVE-type containing 26.
   
 
 0.996
AP5B1
Adaptor related protein complex 5 subunit beta 1.
    
 
 0.986
AP5M1
Adaptor related protein complex 5 subunit mu 1.
    
 
 0.982
AP5Z1
Adaptor related protein complex 5 subunit zeta 1.
    
 
 0.980
AP5S1
Adaptor related protein complex 5 subunit sigma 1.
    
 
 0.967
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.778
SPG21
SPG21 abhydrolase domain containing, maspardin.
      
 0.754
PINK1
PTEN induced kinase 1.
      
 0.694
SIGMAR1
Sigma non-opioid intracellular receptor 1.
      
 0.691
VPS13C
Vacuolar protein sorting 13 homolog C.
   
  
 0.671
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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