SCN1A protein (Catagonus wagneri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SCN1A

Sodium voltage-gated channel alpha subunit 1. (2009 aa)

Predicted Functional Partners:

SCN1B

0.988

SCN4B

0.965

SCN2B

0.955

SCN5A

0.941

UNC79

0.937

PRKACB

0.926

PRKACA

0.926

GNG8

0.904

SCN3B

0.898

ENSCWAP00000017155

0.894

Your Current Organism:

Catagonus wagneri

NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCWAP00000017155	GNG8	ENSCWAP00000017155	ENSCWAP00000013357	annotation not available	G protein subunit gamma 8.	0.660
ENSCWAP00000017155	PRKACA	ENSCWAP00000017155	ENSCWAP00000008453	annotation not available	Protein kinase cAMP-activated catalytic subunit alpha.	0.867
ENSCWAP00000017155	PRKACB	ENSCWAP00000017155	ENSCWAP00000004861	annotation not available	Protein kinase cAMP-activated catalytic subunit beta.	0.893
ENSCWAP00000017155	SCN1A	ENSCWAP00000017155	ENSCWAP00000005320	annotation not available	Sodium voltage-gated channel alpha subunit 1.	0.894
ENSCWAP00000017155	SCN5A	ENSCWAP00000017155	ENSCWAP00000028993	annotation not available	Sodium voltage-gated channel alpha subunit 5.	0.583
GNG8	ENSCWAP00000017155	ENSCWAP00000013357	ENSCWAP00000017155	G protein subunit gamma 8.	annotation not available	0.660
GNG8	PRKACA	ENSCWAP00000013357	ENSCWAP00000008453	G protein subunit gamma 8.	Protein kinase cAMP-activated catalytic subunit alpha.	0.866
GNG8	PRKACB	ENSCWAP00000013357	ENSCWAP00000004861	G protein subunit gamma 8.	Protein kinase cAMP-activated catalytic subunit beta.	0.871
GNG8	SCN1A	ENSCWAP00000013357	ENSCWAP00000005320	G protein subunit gamma 8.	Sodium voltage-gated channel alpha subunit 1.	0.904
GNG8	SCN5A	ENSCWAP00000013357	ENSCWAP00000028993	G protein subunit gamma 8.	Sodium voltage-gated channel alpha subunit 5.	0.763
PRKACA	ENSCWAP00000017155	ENSCWAP00000008453	ENSCWAP00000017155	Protein kinase cAMP-activated catalytic subunit alpha.	annotation not available	0.867
PRKACA	GNG8	ENSCWAP00000008453	ENSCWAP00000013357	Protein kinase cAMP-activated catalytic subunit alpha.	G protein subunit gamma 8.	0.866
PRKACA	PRKACB	ENSCWAP00000008453	ENSCWAP00000004861	Protein kinase cAMP-activated catalytic subunit alpha.	Protein kinase cAMP-activated catalytic subunit beta.	0.947
PRKACA	SCN1A	ENSCWAP00000008453	ENSCWAP00000005320	Protein kinase cAMP-activated catalytic subunit alpha.	Sodium voltage-gated channel alpha subunit 1.	0.926
PRKACA	SCN1B	ENSCWAP00000008453	ENSCWAP00000000141	Protein kinase cAMP-activated catalytic subunit alpha.	Sodium voltage-gated channel beta subunit 1.	0.890
PRKACA	SCN3B	ENSCWAP00000008453	ENSCWAP00000002952	Protein kinase cAMP-activated catalytic subunit alpha.	Sodium voltage-gated channel beta subunit 3.	0.760
PRKACA	SCN4B	ENSCWAP00000008453	ENSCWAP00000007631	Protein kinase cAMP-activated catalytic subunit alpha.	Sodium voltage-gated channel beta subunit 4.	0.890
PRKACA	SCN5A	ENSCWAP00000008453	ENSCWAP00000028993	Protein kinase cAMP-activated catalytic subunit alpha.	Sodium voltage-gated channel alpha subunit 5.	0.933
PRKACB	ENSCWAP00000017155	ENSCWAP00000004861	ENSCWAP00000017155	Protein kinase cAMP-activated catalytic subunit beta.	annotation not available	0.893
PRKACB	GNG8	ENSCWAP00000004861	ENSCWAP00000013357	Protein kinase cAMP-activated catalytic subunit beta.	G protein subunit gamma 8.	0.871