Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRS3Fibroblast growth factor receptor substrate 3. (494 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.987
ENSCWAP00000006133
annotation not available
    
 0.940
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.940
CRK
CRK proto-oncogene, adaptor protein.
    
 0.896
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.893
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.890
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.885
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.881
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
   
 0.879
NTRK1
Neurotrophic receptor tyrosine kinase 1.
    
 0.864
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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