STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4416 aa)    
Predicted Functional Partners:
UBB
Ubiquitin B.
    
 0.985
MFN2
Mitofusin 2.
    
 0.984
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.981
AMBRA1
Autophagy and beclin 1 regulator 1.
    
 0.980
USP7
Ubiquitin specific peptidase 7.
   
 
 0.974
TP53
Tumor protein p53.
    
 
 0.972
UBE2D1
Ubiquitin conjugating enzyme E2 D1.
    
 0.965
ENSCWAP00000006692
annotation not available
    
 0.964
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
 
 0.964
RPS27A
Ribosomal protein S27a.
    
 0.964
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.