PKM protein (Catagonus wagneri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PKM

Pyruvate kinase M1/2. (531 aa)

Predicted Functional Partners:

ENO1

0.985

GPI

0.984

ENO3

0.980

ENO2

0.980

ENO4

0.967

TKTL1

0.965

TKT

0.965

H6PD

0.964

PC

0.962

LDHB

0.958

Your Current Organism:

Catagonus wagneri

NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENO1	ENO2	ENSCWAP00000005499	ENSCWAP00000006631	Enolase 1.	Enolase 2.	0.947
ENO1	ENO3	ENSCWAP00000005499	ENSCWAP00000001691	Enolase 1.	Enolase 3.	0.947
ENO1	ENO4	ENSCWAP00000005499	ENSCWAP00000025896	Enolase 1.	Enolase 4.	0.937
ENO1	GPI	ENSCWAP00000005499	ENSCWAP00000000825	Enolase 1.	Glucose-6-phosphate isomerase.	0.992
ENO1	H6PD	ENSCWAP00000005499	ENSCWAP00000005853	Enolase 1.	Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.	0.936
ENO1	LDHB	ENSCWAP00000005499	ENSCWAP00000024143	Enolase 1.	Lactate dehydrogenase B.	0.560
ENO1	PKM	ENSCWAP00000005499	ENSCWAP00000005595	Enolase 1.	Pyruvate kinase M1/2.	0.985
ENO1	TKT	ENSCWAP00000005499	ENSCWAP00000023167	Enolase 1.	Transketolase.	0.972
ENO1	TKTL1	ENSCWAP00000005499	ENSCWAP00000011298	Enolase 1.	Transketolase like 1.	0.971
ENO2	ENO1	ENSCWAP00000006631	ENSCWAP00000005499	Enolase 2.	Enolase 1.	0.947
ENO2	ENO3	ENSCWAP00000006631	ENSCWAP00000001691	Enolase 2.	Enolase 3.	0.947
ENO2	ENO4	ENSCWAP00000006631	ENSCWAP00000025896	Enolase 2.	Enolase 4.	0.938
ENO2	GPI	ENSCWAP00000006631	ENSCWAP00000000825	Enolase 2.	Glucose-6-phosphate isomerase.	0.992
ENO2	H6PD	ENSCWAP00000006631	ENSCWAP00000005853	Enolase 2.	Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.	0.936
ENO2	LDHB	ENSCWAP00000006631	ENSCWAP00000024143	Enolase 2.	Lactate dehydrogenase B.	0.478
ENO2	PKM	ENSCWAP00000006631	ENSCWAP00000005595	Enolase 2.	Pyruvate kinase M1/2.	0.980
ENO2	TKT	ENSCWAP00000006631	ENSCWAP00000023167	Enolase 2.	Transketolase.	0.971
ENO2	TKTL1	ENSCWAP00000006631	ENSCWAP00000011298	Enolase 2.	Transketolase like 1.	0.971
ENO3	ENO1	ENSCWAP00000001691	ENSCWAP00000005499	Enolase 3.	Enolase 1.	0.947
ENO3	ENO2	ENSCWAP00000001691	ENSCWAP00000006631	Enolase 3.	Enolase 2.	0.947