Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP53Tumor protein p53. (386 aa)    
Predicted Functional Partners:
ATM
ATM serine/threonine kinase.
    
 0.999
MDM2
MDM2 proto-oncogene.
   
 0.999
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.998
BCL2
BCL2 apoptosis regulator.
    
 0.998
CHEK2
Checkpoint kinase 2.
    
 0.998
SMYD2
SET and MYND domain containing 2.
    
 0.998
SIRT1
Sirtuin 1.
    
 0.998
CHEK1
Checkpoint kinase 1.
    
 0.997
AURKA
Aurora kinase A.
    
 0.997
CREBBP
CREB binding protein.
    
 0.997
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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