Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IDEInsulin degrading enzyme. (1019 aa)    
Predicted Functional Partners:
INS
Insulin.
    
 0.973
ENSCWAP00000013710
annotation not available
    
 0.968
NRDC
Nardilysin convertase.
   
 
 0.953
PPCS
Phosphopantothenoylcysteine synthetase.
    
   0.943
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.936
APP
Amyloid beta precursor protein.
    
 
 0.928
NPPA
Natriuretic peptide A.
    
 
 0.922
UBB
Ubiquitin B.
    
  0.915
IGF2
Insulin like growth factor 2.
    
 
 0.914
BACE1
Beta-secretase 1.
     
 0.908
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.