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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TREM2Triggering receptor expressed on myeloid cells 2. (216 aa)    
Predicted Functional Partners:
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.999
APOE
Apolipoprotein E.
   
 
 0.963
SYK
Spleen associated tyrosine kinase.
   
 
 0.949
AXL
AXL receptor tyrosine kinase.
     
 0.872
C1QA
Complement C1q A chain.
   
  
 0.865
P2RY12
Purinergic receptor P2Y12.
      
 0.842
PLCG2
Phospholipase C gamma 2.
     
 0.838
TMEM119
Transmembrane protein 119.
      
 0.832
TREML2
Triggering receptor expressed on myeloid cells like 2.
   
 
 0.803
ENSCWAP00000005868
annotation not available
     
 0.801
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.