Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TREM2Triggering receptor expressed on myeloid cells 2. (216 aa)    
Predicted Functional Partners:
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.996
APOE
Apolipoprotein E.
   
 
 0.975
SYK
Spleen associated tyrosine kinase.
   
 
 0.951
C1QA
Complement C1q A chain.
   
  
 0.913
ENSCWAP00000005868
annotation not available
     
 0.901
MERTK
MER proto-oncogene, tyrosine kinase.
     
 0.888
CX3CR1
C-X3-C motif chemokine receptor 1.
      
 0.887
ENSCWAP00000013586
annotation not available
     
 0.884
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
   
 
 0.879
TREML2
Triggering receptor expressed on myeloid cells like 2.
   
 
 0.870
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.