STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BACE1Beta-secretase 1. (501 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.996
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.976
RTN3
Reticulon 3.
    
 0.965
RTN4
Reticulon 4.
    
 0.959
APLP2
Amyloid beta precursor like protein 2.
    
 0.942
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
    
 0.939
IDE
Insulin degrading enzyme.
     
 0.908
BACE2
Beta-secretase 2.
     
  0.890
ADAM10
ADAM metallopeptidase domain 10.
    
 
 0.889
APLP1
Amyloid beta precursor like protein 1.
    
 0.880
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.