Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF223Ring finger protein 223. (270 aa)    
Predicted Functional Partners:
KLHL17
Kelch like family member 17.
    
 
 0.625
RNF130
Ring finger protein 130.
      
 0.619
RNF144A
Ring finger protein 144A.
    
 
 0.617
TMEM129
Transmembrane protein 129.
      
 0.599
RNF144B
Ring finger protein 144B.
    
 
 0.598
MEAF6
MYST/Esa1 associated factor 6.
     
 0.594
UBB
Ubiquitin B.
    
  0.593
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
      
 0.583
ICOS
Inducible T cell costimulator.
    
 0.558
ENSCWAP00000023340
annotation not available
    
  0.556
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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