STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP2Caspase 2. (446 aa)    
Predicted Functional Partners:
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain.
    
 0.992
BID
BH3 interacting domain death agonist.
    
 0.975
CASP3
Caspase 3.
    
 0.968
APAF1
Apoptotic peptidase activating factor 1.
    
 0.934
ENSCWAP00000014093
annotation not available
   
 0.932
CASP8
Caspase 8.
   
 0.932
XIAP
X-linked inhibitor of apoptosis.
   
 0.874
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 0.862
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.862
TRADD
TNFRSF1A associated via death domain.
    
 0.821
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.