Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRF5Interferon regulatory factor 5. (501 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor associated factor 6.
    
 0.989
CREBBP
CREB binding protein.
    
 0.926
ENSCWAP00000010244
annotation not available
     
 0.885
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.860
ENSCWAP00000010139
annotation not available
     
 0.853
RELA
RELA proto-oncogene, NF-kB subunit.
   
 
 0.822
IL6
Interleukin 6.
   
 0.814
IRF1
Interferon regulatory factor 1.
    
 0.798
TBK1
TANK binding kinase 1.
    
 0.798
STAT1
Signal transducer and activator of transcription 1.
    
 0.797
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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