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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1199 aa)    
Predicted Functional Partners:
SCN2A
Sodium voltage-gated channel alpha subunit 2.
    
 0.906
HCN1
Hyperpolarization activated cyclic nucleotide gated potassium channel 1.
  
  
 
0.875
HCN3
Hyperpolarization activated cyclic nucleotide gated potassium channel 3.
  
 
0.865
HCN2
Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.
  
  
 
0.856
KCNE2
Potassium voltage-gated channel subfamily E regulatory subunit 2.
    
 0.808
SCN5A
Sodium voltage-gated channel alpha subunit 5.
    
 0.800
SCN1A
Sodium voltage-gated channel alpha subunit 1.
    
 0.715
KCNE5
Potassium voltage-gated channel subfamily E regulatory subunit 5.
     
 0.714
SYT2
Synaptotagmin 2.
      
 0.692
TBX18
T-box transcription factor 18.
      
 0.691
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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