Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1199 aa)    
Predicted Functional Partners:
HCN2
Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.
  
  
 
0.947
HCN3
Hyperpolarization activated cyclic nucleotide gated potassium channel 3.
  
 
0.944
SCN2A
Sodium voltage-gated channel alpha subunit 2.
    
 0.899
SCN5A
Sodium voltage-gated channel alpha subunit 5.
    
 0.814
HCN1
Hyperpolarization activated cyclic nucleotide gated potassium channel 1.
  
  
 
0.751
KCNE2
Potassium voltage-gated channel subfamily E regulatory subunit 2.
    
 0.739
KCNE5
Potassium voltage-gated channel subfamily E regulatory subunit 5.
     
 0.716
CACNA1C
Calcium voltage-gated channel subunit alpha1 C.
    
 0.648
SHOX2
Short stature homeobox 2.
    
 
 0.633
SCN1A
Sodium voltage-gated channel alpha subunit 1.
    
 0.609
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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