Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TPH2Tryptophan hydroxylase 2. (459 aa)    
Predicted Functional Partners:
TPH1
Tryptophan hydroxylase 1.
    
  0.984
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.974
PCBD1
Pterin-4 alpha-carbinolamine dehydratase 1.
  
 0.974
IDO2
Indoleamine 2,3-dioxygenase 2.
   
 
 0.970
IDO1
Indoleamine 2,3-dioxygenase 1.
   
 
 0.956
DDC
Dopa decarboxylase.
   
 0.953
QDPR
Quinoid dihydropteridine reductase.
  
 
 0.943
SPR
Sepiapterin reductase.
     
 0.936
TDO2
Tryptophan 2,3-dioxygenase.
  
 
 0.936
TAT
Tyrosine aminotransferase.
   
 
 0.896
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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