Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXO1Forkhead box O1. (655 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 0.992
CREBBP
CREB binding protein.
   
 0.991
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.979
AKT3
AKT serine/threonine kinase 3.
    
 0.976
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta.
    
 0.973
PPARGC1A
PPARG coactivator 1 alpha.
    
 0.967
SGK1
Serum/glucocorticoid regulated kinase 1.
    
 0.966
AKT2
AKT serine/threonine kinase 2.
    
 0.962
AKT1
AKT serine/threonine kinase 1.
    
 0.962
SGK2
Serum/glucocorticoid regulated kinase 2.
    
 0.962
Your Current Organism:
Catagonus wagneri
NCBI taxonomy Id: 51154
Other names: C. wagneri, Chacoan peccary
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