| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CFPG_034 | CFPG_035 | CFPG_034 | CFPG_035 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.783 |
| CFPG_034 | hisB | CFPG_034 | CFPG_033 | Conserved hypothetical protein. | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.556 |
| CFPG_034 | hisC | CFPG_034 | CFPG_032 | Conserved hypothetical protein. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.556 |
| CFPG_034 | hisD | CFPG_034 | CFPG_031 | Conserved hypothetical protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.438 |
| CFPG_034 | hisG | CFPG_034 | CFPG_030 | Conserved hypothetical protein. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.425 |
| CFPG_034 | hisH | CFPG_034 | CFPG_037 | Conserved hypothetical protein. | Imidazole glycerol phosphate synthase glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.414 |
| CFPG_034 | rny | CFPG_034 | CFPG_036 | Conserved hypothetical protein. | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay. | 0.545 |
| CFPG_035 | CFPG_034 | CFPG_035 | CFPG_034 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.783 |
| CFPG_035 | hisB | CFPG_035 | CFPG_033 | Conserved hypothetical protein. | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.590 |
| CFPG_035 | hisC | CFPG_035 | CFPG_032 | Conserved hypothetical protein. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.552 |
| CFPG_035 | hisD | CFPG_035 | CFPG_031 | Conserved hypothetical protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.444 |
| CFPG_035 | hisG | CFPG_035 | CFPG_030 | Conserved hypothetical protein. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.445 |
| CFPG_035 | hisH | CFPG_035 | CFPG_037 | Conserved hypothetical protein. | Imidazole glycerol phosphate synthase glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.416 |
| CFPG_035 | rny | CFPG_035 | CFPG_036 | Conserved hypothetical protein. | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay. | 0.548 |
| hisB | CFPG_034 | CFPG_033 | CFPG_034 | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Conserved hypothetical protein. | 0.556 |
| hisB | CFPG_035 | CFPG_033 | CFPG_035 | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Conserved hypothetical protein. | 0.590 |
| hisB | hisC | CFPG_033 | CFPG_032 | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.999 |
| hisB | hisD | CFPG_033 | CFPG_031 | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
| hisB | hisG | CFPG_033 | CFPG_030 | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.999 |
| hisB | hisH | CFPG_033 | CFPG_037 | Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Imidazole glycerol phosphate synthase glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |