node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CFPG_252 | guaA | CFPG_252 | CFPG_572 | Ribose-phosphate pyrophosphokinase. | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.618 |
CFPG_252 | pth | CFPG_252 | CFPG_131 | Ribose-phosphate pyrophosphokinase. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.446 |
CFPG_252 | rplY | CFPG_252 | CFPG_132 | Ribose-phosphate pyrophosphokinase. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.712 |
CFPG_252 | ychF | CFPG_252 | CFPG_270 | Ribose-phosphate pyrophosphokinase. | Putative translation factor EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.533 |
CFPG_511 | guaA | CFPG_511 | CFPG_572 | Peptide chain release factor 2. | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.445 |
CFPG_511 | mfd | CFPG_511 | CFPG_225 | Peptide chain release factor 2. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.603 |
CFPG_511 | pth | CFPG_511 | CFPG_131 | Peptide chain release factor 2. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.486 |
CFPG_511 | rplY | CFPG_511 | CFPG_132 | Peptide chain release factor 2. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.611 |
guaA | CFPG_252 | CFPG_572 | CFPG_252 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase. | 0.618 |
guaA | CFPG_511 | CFPG_572 | CFPG_511 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Peptide chain release factor 2. | 0.445 |
guaA | pheT | CFPG_572 | CFPG_580 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.844 |
guaA | polA | CFPG_572 | CFPG_268 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.632 |
guaA | pth | CFPG_572 | CFPG_131 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.482 |
guaA | tilS | CFPG_572 | CFPG_004 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.403 |
guaA | ychF | CFPG_572 | CFPG_270 | Glutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative translation factor EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.688 |
ispH | pth | CFPG_127 | CFPG_131 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.457 |
mfd | CFPG_511 | CFPG_225 | CFPG_511 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptide chain release factor 2. | 0.603 |
mfd | polA | CFPG_225 | CFPG_268 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.535 |
mfd | pth | CFPG_225 | CFPG_131 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.518 |
mfd | tilS | CFPG_225 | CFPG_004 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.472 |