| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CFPG_144 | CFPG_145 | CFPG_144 | CFPG_145 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.949 |
| CFPG_144 | CFPG_180 | CFPG_144 | CFPG_180 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | 0.575 |
| CFPG_144 | dnaJ | CFPG_144 | CFPG_298 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.974 |
| CFPG_144 | dnaK | CFPG_144 | CFPG_516 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.981 |
| CFPG_144 | groL | CFPG_144 | CFPG_289 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.919 |
| CFPG_144 | groS | CFPG_144 | CFPG_288 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.814 |
| CFPG_144 | grpE | CFPG_144 | CFPG_299 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.720 |
| CFPG_144 | lon | CFPG_144 | CFPG_156 | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.664 |
| CFPG_145 | CFPG_144 | CFPG_145 | CFPG_144 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.949 |
| CFPG_145 | CFPG_180 | CFPG_145 | CFPG_180 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | 0.878 |
| CFPG_145 | CFPG_735 | CFPG_145 | CFPG_735 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Ste24-like endopeptidase. | 0.445 |
| CFPG_145 | dnaJ | CFPG_145 | CFPG_298 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.798 |
| CFPG_145 | dnaK | CFPG_145 | CFPG_516 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.982 |
| CFPG_145 | groL | CFPG_145 | CFPG_289 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.553 |
| CFPG_145 | groS | CFPG_145 | CFPG_288 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.571 |
| CFPG_145 | grpE | CFPG_145 | CFPG_299 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.803 |
| CFPG_145 | lon | CFPG_145 | CFPG_156 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.646 |
| CFPG_180 | CFPG_144 | CFPG_180 | CFPG_144 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.575 |
| CFPG_180 | CFPG_145 | CFPG_180 | CFPG_145 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.878 |
| CFPG_180 | dnaJ | CFPG_180 | CFPG_298 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.565 |
