Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYG_01417
Hypothetical protein; Belongs to the SOS response-associated peptidase family. (253 aa)
Predicted Functional Partners:
KYG_01412
COG1960 Acyl-CoA dehydrogenases.
0.512
KYG_00942
COG0582 Integrase; Belongs to the 'phage' integrase family.
0.400
Your Current Organism:
Nocardioides sp. SLBN35
NCBI taxonomy Id: 512030 Other names: Acidovorax sp. NO1, N. sp. SLBN-35, Nocardioides sp. SLBN-35