node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KYG_02092 | KYG_02097 | KYG_02092 | KYG_02097 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.714 |
KYG_02092 | KYG_02102 | KYG_02092 | KYG_02102 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG1960 Acyl-CoA dehydrogenases. | 0.958 |
KYG_02092 | aceK | KYG_02092 | KYG_02087 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | 0.746 |
KYG_02097 | KYG_02092 | KYG_02097 | KYG_02092 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.714 |
KYG_02097 | KYG_02102 | KYG_02097 | KYG_02102 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG1960 Acyl-CoA dehydrogenases. | 0.658 |
KYG_02097 | KYG_02107 | KYG_02097 | KYG_02107 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG0642 Signal transduction histidine kinase. | 0.536 |
KYG_02097 | KYG_06244 | KYG_02097 | KYG_06244 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.532 |
KYG_02097 | KYG_08255 | KYG_02097 | KYG_08255 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.510 |
KYG_02097 | KYG_12624 | KYG_02097 | KYG_12624 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG0067 Glutamate synthase domain 1. | 0.762 |
KYG_02097 | KYG_16617 | KYG_02097 | KYG_16617 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Peptidylprolyl isomerase; COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1. | 0.481 |
KYG_02097 | aceK | KYG_02097 | KYG_02087 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | 0.517 |
KYG_02097 | fabH | KYG_02097 | KYG_06249 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.541 |
KYG_02097 | fabZ | KYG_02097 | KYG_20515 | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.492 |
KYG_02102 | KYG_02092 | KYG_02102 | KYG_02092 | COG1960 Acyl-CoA dehydrogenases. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.958 |
KYG_02102 | KYG_02097 | KYG_02102 | KYG_02097 | COG1960 Acyl-CoA dehydrogenases. | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.658 |
KYG_02102 | KYG_02107 | KYG_02102 | KYG_02107 | COG1960 Acyl-CoA dehydrogenases. | COG0642 Signal transduction histidine kinase. | 0.629 |
KYG_02107 | KYG_02097 | KYG_02107 | KYG_02097 | COG0642 Signal transduction histidine kinase. | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.536 |
KYG_02107 | KYG_02102 | KYG_02107 | KYG_02102 | COG0642 Signal transduction histidine kinase. | COG1960 Acyl-CoA dehydrogenases. | 0.629 |
KYG_02107 | KYG_12624 | KYG_02107 | KYG_12624 | COG0642 Signal transduction histidine kinase. | COG0067 Glutamate synthase domain 1. | 0.432 |
KYG_06244 | KYG_02097 | KYG_06244 | KYG_02097 | COG0331 (acyl-carrier-protein) S-malonyltransferase. | Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.532 |