STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYG_02852HhH-GPD family protein; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. (223 aa)    
Predicted Functional Partners:
KYG_21329
Ada metal-binding domain-containing protein; COG2169 Adenosine deaminase.
 
  
0.922
KYG_08260
COG0350 Methylated DNA-protein cysteine methyltransferase.
 
 
 0.913
KYG_21334
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
 
 0.892
KYG_21509
O6-methylguanine-DNA methyltransferase/Ada regulatory protein; COG2169 Adenosine deaminase.
 
 
 0.820
KYG_04220
Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.
   
 0.781
KYG_04499
Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.
   
 0.781
KYG_23845
Exodeoxyribonuclease III Xth; COG0708 Exonuclease III.
   
 0.781
cysS
COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.748
accA
acetyl-CoA carboxylase, carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
       0.686
KYG_02842
Hypothetical protein; COG0457 FOG: TPR repeat.
 
     0.616
Your Current Organism:
Nocardioides sp. SLBN35
NCBI taxonomy Id: 512030
Other names: Acidovorax sp. NO1, N. sp. SLBN-35, Nocardioides sp. SLBN-35
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