STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBCOG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. (316 aa)    
Predicted Functional Partners:
KYG_18306
COG0460 Homoserine dehydrogenase.
 
  
 0.966
KYG_18311
COG0498 Threonine synthase.
    
 0.960
KYG_10020
COG0460 Homoserine dehydrogenase.
 
  
 0.924
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.874
KYG_07266
COG2873 O-acetylhomoserine sulfhydrylase.
    
  0.868
KYG_20380
COG2873 O-acetylhomoserine sulfhydrylase.
    
  0.868
KYG_04944
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.867
KYG_09210
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
    
  0.867
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.867
KYG_08835
COG2873 O-acetylhomoserine sulfhydrylase.
    
  0.833
Your Current Organism:
Nocardioides sp. SLBN35
NCBI taxonomy Id: 512030
Other names: Acidovorax sp. NO1, N. sp. SLBN-35, Nocardioides sp. SLBN-35
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.