STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYG_03131Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (410 aa)    
Predicted Functional Partners:
KYG_05159
COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.973
KYG_18596
Pyridoxal-5'-phosphate-dependent enzyme subunit beta; COG0031 Cysteine synthase.
  
 0.965
KYG_09210
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
  
 
 0.958
KYG_20380
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
0.940
KYG_07266
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
0.939
KYG_04944
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.933
KYG_08835
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
0.930
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.930
KYG_00195
COG2897 Rhodanese-related sulfurtransferase.
 
 
 0.929
KYG_10225
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent).
  
 
 0.917
Your Current Organism:
Nocardioides sp. SLBN35
NCBI taxonomy Id: 512030
Other names: Acidovorax sp. NO1, N. sp. SLBN-35, Nocardioides sp. SLBN-35
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.