STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYG_05304Hypothetical protein; COG1694 Predicted pyrophosphatase. (118 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.782
KYG_16395
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
  0.763
KYG_00937
COG0209 Ribonucleotide reductase, alpha subunit.
    
  0.720
KYG_02007
COG0209 Ribonucleotide reductase, alpha subunit.
    
  0.710
aroA
Bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidine monophosphate kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
    
  0.591
KYG_05309
NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.583
KYG_16400
Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
  
  0.562
ndk
Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.500
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
    
  0.486
KYG_09265
COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase.
    
  0.477
Your Current Organism:
Nocardioides sp. SLBN35
NCBI taxonomy Id: 512030
Other names: Acidovorax sp. NO1, N. sp. SLBN-35, Nocardioides sp. SLBN-35
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