node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KYG_02722 | KYG_03541 | KYG_02722 | KYG_03541 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | 0.691 |
KYG_02722 | KYG_07356 | KYG_02722 | KYG_07356 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. | 0.992 |
KYG_02722 | KYG_07366 | KYG_02722 | KYG_07366 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | COG2104 Sulfur transfer protein involved in thiamine biosynthesis. | 0.877 |
KYG_02722 | KYG_07376 | KYG_02722 | KYG_07376 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.964 |
KYG_02722 | KYG_18416 | KYG_02722 | KYG_18416 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.496 |
KYG_02722 | thiC | KYG_02722 | KYG_04979 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.993 |
KYG_02722 | thiG | KYG_02722 | KYG_07361 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.859 |
KYG_02722 | thiL | KYG_02722 | KYG_19756 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.543 |
KYG_02722 | truA | KYG_02722 | KYG_06074 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.504 |
KYG_03541 | KYG_02722 | KYG_03541 | KYG_02722 | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.691 |
KYG_03541 | KYG_07356 | KYG_03541 | KYG_07356 | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. | 0.886 |
KYG_03541 | KYG_07366 | KYG_03541 | KYG_07366 | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | COG2104 Sulfur transfer protein involved in thiamine biosynthesis. | 0.990 |
KYG_03541 | KYG_07376 | KYG_03541 | KYG_07376 | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.717 |
KYG_03541 | KYG_18416 | KYG_03541 | KYG_18416 | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.508 |
KYG_03541 | thiC | KYG_03541 | KYG_04979 | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.875 |
KYG_03541 | thiG | KYG_03541 | KYG_07361 | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.975 |
KYG_07356 | KYG_02722 | KYG_07356 | KYG_02722 | Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.992 |
KYG_07356 | KYG_03541 | KYG_07356 | KYG_03541 | Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. | UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. | 0.886 |
KYG_07356 | KYG_07366 | KYG_07356 | KYG_07366 | Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. | COG2104 Sulfur transfer protein involved in thiamine biosynthesis. | 0.984 |
KYG_07356 | KYG_07371 | KYG_07356 | KYG_07371 | Thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase. | FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.943 |