node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KYG_09555 | KYG_09560 | KYG_09555 | KYG_09560 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.991 |
KYG_09555 | KYG_21314 | KYG_09555 | KYG_21314 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.782 |
KYG_09555 | kdsA | KYG_09555 | KYG_16827 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.993 |
KYG_09555 | kdsB | KYG_09555 | KYG_16050 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.990 |
KYG_09555 | lpxA | KYG_09555 | KYG_20520 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.734 |
KYG_09555 | lpxB | KYG_09555 | KYG_20525 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | Lipid-a-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.725 |
KYG_09555 | lpxC | KYG_09555 | KYG_04989 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.764 |
KYG_09555 | lpxD | KYG_09555 | KYG_20510 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.707 |
KYG_09555 | lpxK | KYG_09555 | KYG_16040 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.729 |
KYG_09560 | KYG_09555 | KYG_09560 | KYG_09555 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | 0.991 |
KYG_09560 | KYG_21314 | KYG_09560 | KYG_21314 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.874 |
KYG_09560 | kdsA | KYG_09560 | KYG_16827 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.991 |
KYG_09560 | kdsB | KYG_09560 | KYG_16050 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.897 |
KYG_09560 | lpxA | KYG_09560 | KYG_20520 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.875 |
KYG_09560 | lpxB | KYG_09560 | KYG_20525 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid-a-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.855 |
KYG_09560 | lpxC | KYG_09560 | KYG_04989 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.867 |
KYG_09560 | lpxD | KYG_09560 | KYG_20510 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.884 |
KYG_09560 | lpxK | KYG_09560 | KYG_16040 | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.878 |
KYG_21314 | KYG_09555 | KYG_21314 | KYG_09555 | 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778 Low specificity phosphatase (HAD superfamily). | 0.782 |
KYG_21314 | KYG_09560 | KYG_21314 | KYG_09560 | 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.874 |