STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYG_17512Class V aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (335 aa)    
Predicted Functional Partners:
hisB
COG0131 Imidazoleglycerol-phosphate dehydratase.
  
 
 0.988
KYG_14853
COG0287 Prephenate dehydrogenase.
  
 
 0.980
KYG_14858
COG1605 Chorismate mutase.
  
 
 0.954
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 
 0.929
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
 
 0.929
hisD
Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.929
KYG_09360
D-amino-acid dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating).
  
  
 0.923
KYG_10420
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
   
 
 0.922
KYG_15590
D-amino-acid dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating).
  
  
 0.917
hisC
COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
  0.915
Your Current Organism:
Nocardioides sp. SLBN35
NCBI taxonomy Id: 512030
Other names: Acidovorax sp. NO1, N. sp. SLBN-35, Nocardioides sp. SLBN-35
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