node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OCT10952.1 | OCT11928.1 | A8709_04415 | A8709_29130 | General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.818 |
OCT10952.1 | OCT15033.1 | A8709_04415 | A8709_13010 | General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.732 |
OCT10952.1 | OCT15897.1 | A8709_04415 | A8709_09745 | General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |
OCT10952.1 | OCT15924.1 | A8709_04415 | A8709_09880 | General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. | 0.438 |
OCT11928.1 | OCT10952.1 | A8709_29130 | A8709_04415 | TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.818 |
OCT11928.1 | OCT15033.1 | A8709_29130 | A8709_13010 | TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.697 |
OCT11928.1 | OCT15897.1 | A8709_29130 | A8709_09745 | TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |
OCT12781.1 | OCT15897.1 | A8709_32150 | A8709_09745 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.845 |
OCT12781.1 | OCT16983.1 | A8709_32150 | A8709_23585 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.475 |
OCT12781.1 | gcvT | A8709_32150 | A8709_04140 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.530 |
OCT12781.1 | thyA | A8709_32150 | A8709_22255 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.887 |
OCT14247.1 | OCT15897.1 | A8709_25795 | A8709_09745 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.755 |
OCT14247.1 | OCT16983.1 | A8709_25795 | A8709_23585 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OCT14247.1 | gcvT | A8709_25795 | A8709_04140 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.940 |
OCT14247.1 | glyA | A8709_25795 | A8709_09750 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
OCT14247.1 | thyA | A8709_25795 | A8709_22255 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.636 |
OCT15033.1 | OCT10952.1 | A8709_13010 | A8709_04415 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.732 |
OCT15033.1 | OCT11928.1 | A8709_13010 | A8709_29130 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.697 |
OCT15033.1 | OCT15897.1 | A8709_13010 | A8709_09745 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |
OCT15897.1 | OCT10952.1 | A8709_09745 | A8709_04415 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |