STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menGUbiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (230 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 0.962
KLO26832.1
fatty-acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.854
KLO29055.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.821
KLO28566.1
Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.806
KLO28278.1
Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.802
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
     
 0.779
KLO30984.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.693
KLO31154.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.693
KLO27848.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.680
KLO29768.1
stearoyl-CoA 9-desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.672
Your Current Organism:
Mycolicibacter heraklionensis
NCBI taxonomy Id: 512402
Other names: CECT 7509, LMG 24735, LMG:24735, M. heraklionensis, Mycobacterium heraklionense, Mycobacterium heraklionense Tortoli et al. 2013, Mycobacterium sp. FI-05158, Mycobacterium sp. FI-06009, Mycobacterium sp. FI-06082, Mycobacterium sp. FI-06150, Mycobacterium sp. FI-06255, Mycobacterium sp. FI-09376, Mycobacterium sp. GN-1, Mycobacterium sp. NCTC 13432, Mycolicibacter heraklionensis (Tortoli et al. 2013) Gupta et al. 2018, NCTC 13432, strain GN-1
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