STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AMIS_19320Putative acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (373 aa)    
Predicted Functional Partners:
AMIS_60620
Putative fatty acid oxidation complex alpha subunit.
 0.999
AMIS_68350
Putative 3-hydroxyacyl-CoA dehydrogenase.
 0.991
AMIS_71840
Putative 3-hydroxyacyl-CoA dehydrogenase.
 0.986
AMIS_25560
Putative acetyl-CoA synthetase.
  
 
 0.932
acsA
Putative acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.932
AMIS_57460
Putative acyl-CoA oxidase.
  
 0.932
AMIS_8480
Putative acyl-CoA synthetase.
  
 
 0.932
AMIS_72800
Putative phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.929
AMIS_35030
Putative 3-oxoadipate CoA transferase subunit B.
  
 
 0.927
AMIS_7250
Putative alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.924
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.