Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMIS_260Putative hydroxymethylglutaryl-CoA lyase. (292 aa)    
Predicted Functional Partners:
AMIS_8480
Putative acyl-CoA synthetase.
 
 
 0.936
AMIS_11710
Putative enoyl-CoA hydratase/isomerase.
  
 
 0.932
AMIS_31070
Putative acetyl-CoA acetyltransferase.
  
 
 0.932
AMIS_75710
Putative 2-oxoglutarate ferredoxin oxidoreductase alpha subunit.
  
 
 0.930
AMIS_35020
Putative 3-oxoadipate CoA transferase subunit A.
  
 
 0.929
AMIS_35030
Putative 3-oxoadipate CoA transferase subunit B.
  
 
 0.927
AMIS_19320
Putative acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
AMIS_19400
Putative acetyl-CoA acetyltransferase.
  
 
 0.921
AMIS_21660
Putative acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
AMIS_50070
Putative acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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