node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMIS_11300 | AMIS_31660 | AMIS_11300 | AMIS_31660 | Putative folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Hypothetical protein; RibD C-terminal domain. | 0.530 |
AMIS_11300 | gcvP | AMIS_11300 | AMIS_42000 | Putative folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Putative glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.579 |
AMIS_11300 | thyA | AMIS_11300 | AMIS_68240 | Putative folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.936 |
AMIS_31660 | AMIS_11300 | AMIS_31660 | AMIS_11300 | Hypothetical protein; RibD C-terminal domain. | Putative folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.530 |
AMIS_31660 | AMIS_31670 | AMIS_31660 | AMIS_31670 | Hypothetical protein; RibD C-terminal domain. | Putative LuxR-family transcriptional regulator. | 0.504 |
AMIS_31660 | AMIS_40400 | AMIS_31660 | AMIS_40400 | Hypothetical protein; RibD C-terminal domain. | Hypothetical protein. | 0.515 |
AMIS_31660 | AMIS_55550 | AMIS_31660 | AMIS_55550 | Hypothetical protein; RibD C-terminal domain. | Hypothetical protein; Activator of Hsp90 ATPase 1 family. | 0.481 |
AMIS_31660 | gcvH | AMIS_31660 | AMIS_46730 | Hypothetical protein; RibD C-terminal domain. | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.530 |
AMIS_31660 | gcvH-2 | AMIS_31660 | AMIS_51850 | Hypothetical protein; RibD C-terminal domain. | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.530 |
AMIS_31660 | gcvP | AMIS_31660 | AMIS_42000 | Hypothetical protein; RibD C-terminal domain. | Putative glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.568 |
AMIS_31660 | gcvT | AMIS_31660 | AMIS_13920 | Hypothetical protein; RibD C-terminal domain. | Putative glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.520 |
AMIS_31660 | gcvT-2 | AMIS_31660 | AMIS_46740 | Hypothetical protein; RibD C-terminal domain. | Putative glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.520 |
AMIS_31660 | thyA | AMIS_31660 | AMIS_68240 | Hypothetical protein; RibD C-terminal domain. | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.752 |
AMIS_31670 | AMIS_31660 | AMIS_31670 | AMIS_31660 | Putative LuxR-family transcriptional regulator. | Hypothetical protein; RibD C-terminal domain. | 0.504 |
AMIS_40400 | AMIS_31660 | AMIS_40400 | AMIS_31660 | Hypothetical protein. | Hypothetical protein; RibD C-terminal domain. | 0.515 |
AMIS_55550 | AMIS_31660 | AMIS_55550 | AMIS_31660 | Hypothetical protein; Activator of Hsp90 ATPase 1 family. | Hypothetical protein; RibD C-terminal domain. | 0.481 |
gcvH | AMIS_31660 | AMIS_46730 | AMIS_31660 | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Hypothetical protein; RibD C-terminal domain. | 0.530 |
gcvH | gcvH-2 | AMIS_46730 | AMIS_51850 | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.905 |
gcvH | gcvP | AMIS_46730 | AMIS_42000 | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | AMIS_46730 | AMIS_13920 | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.998 |