STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMIS_3340Putative DNA polymerase III delta prime subunit. (397 aa)    
Predicted Functional Partners:
AMIS_11600
Putative DNA polymerase III delta subunit.
 
 
 0.997
AMIS_73580
Putative MerR-family transcriptional regulator.
   
 0.994
dnaN
Putative DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...]
 
 
 0.985
AMIS_15380
Putative DNA polymerase III alpha subunit.
 
 0.984
AMIS_14290
Putative DNA polymerase III epsilon subunit.
 
 0.966
AMIS_78520
Putative DNA polymerase III gamma and tau subunit.
  
  
 
0.924
AMIS_10710
Putative single-strand DNA-binding protein.
 
 
 
 0.867
AMIS_80900
Putative single-stranded DNA-binding protein.
 
 
 
 0.840
dnaE2
Putative DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
  
 
 0.820
AMIS_73490
Putative ATP-dependent DNA helicase.
 
  
 0.782
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.