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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMIS_36680Putative protocatechuate 3,4-dioxygenase alpha subunit. (187 aa)    
Predicted Functional Partners:
AMIS_36670
Putative protocatechuate 3,4-dioxygenase beta subunit.
 
 
0.999
AMIS_36690
Putative 3-carboxy-cis,cis-muconate cycloisomerase.
 
 
 0.998
AMIS_36650
Hypothetical protein; FAD-binding domain.
 
 
 0.989
AMIS_36700
Putative 3-oxoadipate enol-lactone hydrolase.
 
  
 0.955
AMIS_45820
Putative ring-cleavage dioxygenase.
    
 0.906
AMIS_66660
Putative sugar phosphate isomerase/epimerase.
 
   
 0.784
aroE
Putative shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
   
 0.707
menC
Putative mandelate racemase/muconate lactonizing enzyme-like protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
  
  
 0.677
AMIS_36660
Putative IclR-family transcriptional regulator.
 
  
 0.648
AMIS_21690
Putative CoA transferase alpha subunit.
  
  
 0.557
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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