STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMIS_59280Hypothetical protein. (285 aa)    
Predicted Functional Partners:
AMIS_59260
Putative RNA polymerase ECF-subfamily sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
       0.773
AMIS_59270
Hypothetical protein.
       0.773
AMIS_59290
Putative TetR-family transcriptional regulator.
 
     0.693
AMIS_42750
Putative erythromycin esterase.
  
   
 0.621
rpoA
Putative RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.588
AMIS_48830
Putative ribosomal RNA adenine N-6-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
  
   
 0.524
AMIS_79790
Putative TetR-family transcriptional regulator.
  
     0.486
AMIS_59240
Putative secreted metallopeptidase.
 
     0.466
AMIS_54430
Putative ATP-dependent helicase.
      
 0.457
metK
Putative S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
      
 0.430
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.