STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMIS_69530Putative M16-family peptidase; Belongs to the peptidase M16 family. (445 aa)    
Predicted Functional Partners:
pnp
Putative guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase alpha chain; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.936
dapB
Putative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
     
 0.912
AMIS_14240
Putative cytochrome b subunit.
    
 0.857
AMIS_58770
Putative NRPS-type-I PKS fusion protein.
  
 
 0.814
AMIS_14230
Putative ubiquinol-cytochrome c reductase iron-sulphur subunit.
   
 0.791
AMIS_16050
Hypothetical protein; Rieske [2Fe-2S] domain.
   
 0.791
AMIS_49720
Hypothetical protein; Condensation domain of NRPS.
  
 
 0.790
nuoG
Putative NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 
 0.780
AMIS_32330
Putative NRPS.
  
 
 0.756
nuoE
Putative NADH dehydrogenase I chain E.
   
 
 0.749
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.