node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMIS_43110 | AMIS_6920 | AMIS_43110 | AMIS_6920 | Putative inositol-5'-monophosphate dehydrogenase. | Putative inosine-5'-monophosphate dehydrogenase. | 0.938 |
AMIS_43110 | AMIS_78050 | AMIS_43110 | AMIS_78050 | Putative inositol-5'-monophosphate dehydrogenase. | Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.937 |
AMIS_43110 | AMIS_9480 | AMIS_43110 | AMIS_9480 | Putative inositol-5'-monophosphate dehydrogenase. | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.964 |
AMIS_43110 | guaA | AMIS_43110 | AMIS_6960 | Putative inositol-5'-monophosphate dehydrogenase. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
AMIS_43110 | guaB | AMIS_43110 | AMIS_6910 | Putative inositol-5'-monophosphate dehydrogenase. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.941 |
AMIS_43110 | pheT | AMIS_43110 | AMIS_61810 | Putative inositol-5'-monophosphate dehydrogenase. | Putative phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.868 |
AMIS_43110 | purD | AMIS_43110 | AMIS_1120 | Putative inositol-5'-monophosphate dehydrogenase. | Putative phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.744 |
AMIS_620 | AMIS_78050 | AMIS_620 | AMIS_78050 | Putative phosphoribosyltransferase. | Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.953 |
AMIS_620 | apt | AMIS_620 | AMIS_62760 | Putative phosphoribosyltransferase. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.912 |
AMIS_620 | gmk | AMIS_620 | AMIS_62090 | Putative phosphoribosyltransferase. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.967 |
AMIS_620 | guaA | AMIS_620 | AMIS_6960 | Putative phosphoribosyltransferase. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.991 |
AMIS_620 | guaB | AMIS_620 | AMIS_6910 | Putative phosphoribosyltransferase. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.503 |
AMIS_620 | pheT | AMIS_620 | AMIS_61810 | Putative phosphoribosyltransferase. | Putative phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.459 |
AMIS_620 | purD | AMIS_620 | AMIS_1120 | Putative phosphoribosyltransferase. | Putative phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.462 |
AMIS_6920 | AMIS_43110 | AMIS_6920 | AMIS_43110 | Putative inosine-5'-monophosphate dehydrogenase. | Putative inositol-5'-monophosphate dehydrogenase. | 0.938 |
AMIS_6920 | AMIS_78050 | AMIS_6920 | AMIS_78050 | Putative inosine-5'-monophosphate dehydrogenase. | Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.917 |
AMIS_6920 | AMIS_9480 | AMIS_6920 | AMIS_9480 | Putative inosine-5'-monophosphate dehydrogenase. | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.926 |
AMIS_6920 | gmk | AMIS_6920 | AMIS_62090 | Putative inosine-5'-monophosphate dehydrogenase. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.402 |
AMIS_6920 | guaA | AMIS_6920 | AMIS_6960 | Putative inosine-5'-monophosphate dehydrogenase. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.997 |
AMIS_6920 | guaB | AMIS_6920 | AMIS_6910 | Putative inosine-5'-monophosphate dehydrogenase. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.992 |