STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMIS_9500Putative histidine ammonia-lyase. (511 aa)    
Predicted Functional Partners:
hutU
Putative urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
Putative imidazolonepropionase.
 
  
 0.993
AMIS_9520
Putative N-formimino-L-glutamate deiminase.
 
  
 0.939
AMIS_51520
Putative phenylalanine/histidine ammonia-lyase.
  
  
 
0.928
AMIS_51560
Putative histidine ammonia-lyase.
  
  
 
0.925
hisD
Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.920
egtD
Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
     
  0.900
AMIS_9530
Putative M20/M25/M40-family peptidase.
     
 0.711
AMIS_9550
Putative RpiR-family transcriptional regulator.
       0.612
gcvP
Putative glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.563
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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