STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgpp1Sphingosine-1-phosphate phosphatase 1. (420 aa)    
Predicted Functional Partners:
Sgpl1
Sphinganine-1-phosphate aldolase.
    
 0.984
Sphk2
Sphingosine kinase 2.
   
 0.963
Asah2
Neutral ceramidase isoform X1.
     
 0.944
Kdsr
3-ketodihydrosphingosine reductase isoform X1.
    
 0.940
Smpd2
Sphingomyelin phosphodiesterase 2.
    
 0.938
Asah1
Acid ceramidase.
    
 0.936
Cers3
Ceramide synthase 3.
    
 0.933
Acer2
Alkaline ceramidase 2 isoform X1.
     
 0.931
Degs1
Sphingolipid delta(4)-desaturase DES1 isoform X1.
     
 0.930
Degs2
Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2.
     
 0.927
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.