STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCCNP00000000379annotation not available (156 aa)    
Predicted Functional Partners:
Wrn
Werner syndrome ATP-dependent helicase.
   
 
 0.996
Xrcc5
LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 5.
   
 0.971
Lig4
DNA ligase 4 isoform X1.
   
 0.948
Mre11a
Double-strand break repair protein MRE11A isoform X1.
   
 0.934
Xrcc6
X-ray repair cross-complementing protein 6.
 
      0.900
Tp53bp1
Tumor suppressor p53-binding protein 1 isoform X1.
    
 0.870
Lig3
DNA ligase 3.
   
 0.841
Aplf
Aprataxin and PNK-like factor isoform X1.
    
 
 0.835
ENSCCNP00000019484
annotation not available
   
 0.833
Tert
Telomerase reverse transcriptase isoform X1.
    
 
 0.789
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.