STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prop1Homeobox protein prophet of Pit-1. (226 aa)    
Predicted Functional Partners:
Crh
Corticotropin-releasing hormone.
      
 0.719
Stat3
Signal transducer and activator of transcription 3 isoform X1.
      
 0.716
Pou1f1
Pituitary-specific positive transcription factor 1 isoform X1.
    
 0.677
Rara
Retinoic acid receptor alpha isoform X1.
      
 0.582
Ghrhr
Growth hormone releasing hormone receptor.
   
  
 0.582
Lhx3
LIM/homeobox protein Lhx3 isoform X1.
   
0.543
Lhx4
LIM/homeobox protein Lhx4.
   
0.490
Ctnnb1
Catenin beta 1.
    
 0.459
Furin
Furin.
    
 
 0.451
Ghrh
LOW QUALITY PROTEIN: somatoliberin.
      
 0.449
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.