STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fen1Flap endonuclease 1. (380 aa)    
Predicted Functional Partners:
Wrn
Werner syndrome ATP-dependent helicase.
  
 0.999
Pcna
Proliferating cell nuclear antigen.
   
 0.999
ENSCCNP00000019484
annotation not available
  
 0.981
Mre11a
Double-strand break repair protein MRE11A isoform X1.
   
 0.973
Pold2
Polymerase (DNA directed), delta 2, regulatory subunit.
   
 0.965
ENSCCNP00000022985
DNA replication ATP-dependent helicase/nuclease DNA2.
   
 0.962
Apex1
LOW QUALITY PROTEIN: DNA-(apurinic or apyrimidinic site) lyase.
   
 0.945
Rfc3
Replication factor C subunit 3/5.
   
 0.942
Rfc4
Replication factor C subunit 2/4.
   
 0.936
Prim1
DNA primase small subunit isoform X1.
   
 
 0.934
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.