STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Enc1Kelch-like protein 25/37 (ectoderm-neural cortex protein). (589 aa)    
Predicted Functional Partners:
Cul3
Cullin-3 isoform X1.
    
 0.790
Kbtbd8
LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 8.
  
 
0.597
Rag1
V(D)J recombination-activating protein 1.
      
 0.577
Hexb
Beta-hexosaminidase subunit beta.
      
 0.570
Cul1
Cullin 1.
    
 0.564
Btbd7
BTB/POZ domain-containing protein 7.
    
 
 0.550
Nedd8
Ubiquitin-like protein Nedd8.
    
 0.547
ENSCCNP00000027691
COMM domain containing 8.
   
 
 0.536
Uba3
NEDD8-activating enzyme E1 catalytic subunit isoform X1.
     
 0.535
Nae1
Amyloid beta precursor protein binding protein 1.
     
 0.532
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.