STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Limk2LOW QUALITY PROTEIN: LIM domain kinase 2. (560 aa)    
Predicted Functional Partners:
Cfl2
Cofilin-2.
   
 0.976
Cfl1
Cofilin-1.
   
 0.971
Pak2
Serine/threonine-protein kinase PAK 2.
    
0.950
Limk1
LIM domain kinase 1 isoform X1.
  
 
 
0.948
ENSCCNP00000023779
Serine/threonine-protein kinase PAK 6.
  
 
0.946
Pak4
Serine/threonine-protein kinase PAK 4.
    
0.942
Pak7
Serine/threonine-protein kinase PAK 5.
    
0.942
Rock2
Rho-associated protein kinase 2 isoform X1.
   
 0.940
Rock1
Rho-associated protein kinase 1 isoform X1.
   
0.939
Rnf185
E3 ubiquitin-protein ligase RNF185 isoform X1.
 
  
 0.785
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.