STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Npm1Nucleophosmin 1. (247 aa)    
Predicted Functional Partners:
Ncl
LOW QUALITY PROTEIN: nucleolin.
   
 
 0.946
ENSCCNP00000018715
Cyclin-dependent kinase 4 inhibitor B-like.
    
 
 0.915
Trp53
Cellular tumor antigen p53 isoform X1.
   
 0.883
Rpl5
60S ribosomal protein L5 isoform X1.
   
 
 0.807
ENSCCNP00000006067
annotation not available
    
 0.770
Npm3
Nucleophosmin 3.
   
 
0.755
Alk
ALK tyrosine kinase receptor.
   
 0.727
Ctcf
Transcriptional repressor CTCF.
    
 0.725
Ago2
Eukaryotic translation initiation factor 2C.
   
 
 0.724
Cenpa
Centromere protein A.
   
 0.686
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.