STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ptch1Protein patched homolog 1. (1398 aa)    
Predicted Functional Partners:
Shh
Sonic hedgehog protein.
   
 0.998
Smo
Smoothened homolog isoform X1.
    
 0.997
Ihh
Indian hedgehog protein.
   
 0.994
Cdon
Cell adhesion molecule-related/down-regulated by oncogenes.
    
 0.988
ENSCCNP00000003071
Desert hedgehog protein.
   
 0.986
Boc
Brother of CDO isoform X1.
    
 0.985
Gas1
LOW QUALITY PROTEIN: growth arrest-specific protein 1.
     
 0.978
Smurf1
E3 ubiquitin-protein ligase SMURF1 isoform X1.
    
 0.970
Smurf2
E3 ubiquitin-protein ligase SMURF2.
    
 0.963
Ptch2
Protein patched homolog 2.
  
  
0.916
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.