STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Wsb1WD repeat and SOCS box-containing protein 1 isoform X1. (421 aa)    
Predicted Functional Partners:
Ash2l
LOW QUALITY PROTEIN: set1/Ash2 histone methyltransferase complex subunit ASH2.
   
 0.835
Cul5
Cullin 5.
    
 0.828
Rbbp5
Retinoblastoma-binding protein 5 isoform X1.
   
0.823
Kansl2
LOW QUALITY PROTEIN: KAT8 regulatory NSL complex subunit 2.
    
 0.786
Setd1b
LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1B.
   
 0.705
Setd1a
[histone H3]-lysine4 N-trimethyltransferase SETD1.
   
 0.705
Hcfc1
Host cell factor 1 isoform X1.
   
 0.701
Hcfc2
Host cell factor 2 isoform X1.
   
 0.701
Rbx1
E3 ubiquitin-protein ligase RBX1.
    
 0.690
Usp20
Ubiquitin carboxyl-terminal hydrolase 20 isoform X1.
   
 
 0.689
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.