STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dot1lHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1450 aa)    
Predicted Functional Partners:
Mllt10
Protein AF-17/10.
    
 
 0.949
Mllt3
YEATS domain-containing protein 1/3.
    
 
 0.911
Mllt1
YEATS domain-containing protein 1/3.
    
 
 0.824
ENSCCNP00000006455
Histone H3.
   
 0.809
Uba52
Ubiquitin-60S ribosomal protein L40 isoform X1.
    
   0.751
Mllt6
Protein AF-17 isoform X1.
    
 
 0.746
Camkmt
Calmodulin-lysine N-methyltransferase.
     
 0.741
ENSCCNP00000026485
annotation not available
    
 
 0.736
Mamld1
Mastermind-like domain-containing protein 1.
      
 0.720
Med8
Mediator of RNA polymerase II transcription subunit 8 isoform X1.
      
 0.720
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.